Active ingredientDorzolamide HydrochlorideCat. No. P-D175-001CAS 130693-82-2
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Impurity or related compound · Dorzolamide family
Pharmaceutical analytical standardDorzolamide Impurity 13 Sodium Salt
- Cat. No.
- P-D175-037
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C20H28N3NaO8S6
- Molecular weight
- 653.81 g/mol
- Category
- Impurity or related compound
Family: Dorzolamide
A carbonic anhydrase inhibitor given as eye drops, approved in the United States in 1994 for glaucoma and ocular hypertension: it reduces the production of aqueous humour and so lowers the pressure inside the eye.
Did you know?It is considered the first medicine to come from structure-based drug design: it was designed by studying the three-dimensional shape of its target, the enzyme carbonic anhydrase II.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dorzolamide family
Active ingredientDorzolamide HydrochlorideCat. No. P-D175-001CAS 130693-82-2
Pharmacopoeial impurity(4R,6S)-Dorzolamide EP Impurity BCat. No. P-D175-002CAS 149249-72-9
Pharmacopoeial impurity(4R,6S)-Dorzolamide EP Impurity B HClCat. No. P-D175-003CAS 1417607-96-5
Pharmacopoeial impurity(4S, 6R)-Dorzolamide EP Impurity BCat. No. P-D175-004CAS 139066-77-6
Pharmacopoeial impurityDorzolamide EP Impurity A HydrochlorideCat. No. P-D175-005CAS 122028-36-8
Pharmacopoeial impurityDorzolamide EP Impurity CCat. No. P-D175-006
Pharmacopoeial impurityDorzolamide EP Impurity C HClCat. No. P-D175-007
Pharmacopoeial impurityDorzolamide EP Impurity ACat. No. P-D175-009CAS 120279-95-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.