Active ingredientDoxorubicinCat. No. P-D184-001CAS 23214-92-8
Drag to rotate
Active ingredient · Doxorubicin family
Pharmaceutical analytical standardDoxorubicin Hydrochloride
Synonyms: Adriacin, Adriamycin hydrochloride, Adriamycin PFS, Adriamycin RDF, Adriablastina cs, Hydroxydaunomycin hydrochloride, Adriamycine, Farmiblastina, Adrimedac, Doxolem, Doxorubin, Urokit Doxo cell, DOXO cell, Doxil (liposomal), Rubex, Hydroxydaunorubicin hydrochloride, Adriblastina, Doxil, Lipodox, Caelyx, Adriblastin, ADM hydrochloride, Adrosal, Duxocin, Doxorubi, Resmycin, Icin Hydrochloride, Adriamycin, Adriblastina hydrochloride
- Cat. No.
- P-D184-002
- CAS
- 25316-40-9
- Alternative CAS
- 23214-92-8 (free base)
- 1392315-46-6 (free base)
- 111266-55-8 (citrate)
- Formula
- C27H29NO11·HCl
- Molecular weight
- 579.98 g/mol
- Category
- Active ingredient (API)
Family: Doxorubicin
An anthracycline antitumour antibiotic obtained in Italy in 1969 from a mutant strain of the bacterium Streptomyces peucetius: it is one of the most widely used chemotherapy drugs, against breast cancer, lymphomas, leukaemias and sarcomas.
Did you know?The original strain of the bacterium was found in a soil sample collected near Castel del Monte, in Apulia: it produced a red pigment, and the medicine itself is a deep red.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Doxorubicin HydrochlorideBP 990
- Doxorubicin hydrochloride CRSEP D2975000
More products in the Doxorubicin family
Active ingredientDoxorubicinCat. No. P-D184-001CAS 23214-92-8
Pharmacopoeial impurityDoxorubicin EP Impurity BCat. No. P-D184-003CAS 106401-68-7
Pharmacopoeial impurityDoxorubicin EP Impurity B HBrCat. No. P-D184-004CAS 148218-14-8
Pharmacopoeial impurityDoxorubicin EP Impurity C HBrCat. No. P-D184-005CAS 60873-68-9
Impurity14-ChlorodaunorubicinCat. No. P-D184-008CAS 121250-06-4
ImpurityDoxorubicin Impurity 1Cat. No. P-D184-010CAS 59325-97-2
ImpurityDoxorubicin Impurity 2Cat. No. P-D184-011CAS 105612-58-6
Impurity7,8-Dehydro-9,10-desacetyldoxorubicinoneCat. No. P-D184-012CAS 64845-67-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.