Active ingredientEbastineCat. No. P-E001-001CAS 90729-43-4
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Pharmacopoeial impurity · Ebastine family
Pharmaceutical analytical standardEbastine EP Impurity C Hydrochloride
Synonyms: 4-(Diphenylmethoxy)piperidinium chloride, Ebastine EP Impurity C HCl, Ebastine Related CoMpound C
- Cat. No.
- P-E001-003
- CAS
- 65214-86-0
- Alternative CAS
- 58258-01-8 (free base)
- Formula
- C18H21NO·HCl
- Molecular weight
- 303.83 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Ebastine
A second-generation H1 antihistamine, patented in 1983 and in use since 1990 mainly for allergic rhinitis and chronic urticaria; little of it enters the brain, so it rarely causes drowsiness.
Did you know?It works mostly through a stand-in: on its first pass through the liver it is converted into carebastine, the molecule that actually carries out the antihistamine action.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ebastine family
Active ingredientEbastineCat. No. P-E001-001CAS 90729-43-4
Pharmacopoeial impurityEbastine EP Impurity BCat. No. P-E001-002CAS 943-27-1
Pharmacopoeial impurityEbastine EP Impurity DCat. No. P-E001-004CAS 97928-18-2
Pharmacopoeial impurityEbastine EP Impurity ECat. No. P-E001-005CAS 1312211-93-0
Pharmacopoeial impurityEbastine EP Impurity E FumarateCat. No. P-E001-006CAS 2734346-74-6
Pharmacopoeial impurityEbastine EP Impurity FCat. No. P-E001-007CAS 1429071-63-5
Pharmacopoeial impurityEbastine EP Impurity F + GCat. No. P-E001-008CAS 1256285-71-8
Pharmacopoeial impurityEbastine EP Impurity GCat. No. P-E001-009CAS 1429071-65-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.