Active ingredientElobixibatCat. No. P-E025-001CAS 439087-18-0
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Impurity or related compound · Elobixibat family
Pharmaceutical analytical standardElobixibat Impurity 5
Synonyms: Methyl (2R)-2-[[2-[(3,3-dibutyl-7-methylsulfanyl-1,1-dioxo-5-phenyl-2,4-dihydro-1lambda6,5-benzothiazepin-8-yl)oxy]acetyl]amino]-2-phenylacetate
- Cat. No.
- P-E025-009
- CAS
- 439088-19-4
- Alternative CAS
- N/A
- Formula
- C35H44N2O6S2
- Molecular weight
- 652.87 g/mol
- Category
- Impurity or related compound
Family: Elobixibat
An ileal bile acid transporter (IBAT) inhibitor, approved in Japan in 2018 for chronic constipation: it was the first drug of this class approved anywhere in the world.
Did you know?It stops the last part of the small intestine from reabsorbing bile acids, so more of them reach the colon, where they draw in water and stimulate bowel movements.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Elobixibat family
Active ingredientElobixibatCat. No. P-E025-001CAS 439087-18-0
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ImpurityElobixibat Acid ImpurityCat. No. P-E025-004CAS 439086-76-7
ImpurityElobixibat Impurity 1Cat. No. P-E025-005
ImpurityElobixibat Impurity 2Cat. No. P-E025-006
ImpurityElobixibat Impurity 3Cat. No. P-E025-007
ImpurityElobixibat Impurity 4Cat. No. P-E025-008CAS 439088-16-1
ImpurityElobixibat Impurity 6Cat. No. P-E025-010CAS 439087-68-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.