Active ingredientElvitegravirCat. No. P-E030-001CAS 697761-98-1
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Metabolite · Elvitegravir family
Pharmaceutical analytical standardElvitegravir Acyl Glucuronide
Synonyms: Elvitegravir Acyl-ss-D-Glucuronide
- Cat. No.
- P-E030-002
- CAS
- 870649-25-5
- Alternative CAS
- N/A
- Formula
- C29H31ClFNO11
- Molecular weight
- 624.01 g/mol
- Category
- Metabolite
Family: Elvitegravir
An inhibitor of HIV integrase, the enzyme that inserts the virus genome into the cell's DNA: approved in the United States in August 2012 in a fixed-dose combination with cobicistat, emtricitabine and tenofovir, in a single tablet.
Did you know?It shares its core structure with the quinolone antibiotics: a chemical scaffold created to hit a bacterial enzyme was adapted to block a viral one.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Elvitegravir family
Active ingredientElvitegravirCat. No. P-E030-001CAS 697761-98-1
Isotopically labelledElvitegravir-d8Cat. No. P-E030-004
Impurity2-Chloro-3-Fluoro ElvitegravirCat. No. P-E030-005CAS 2726921-70-4
ImpurityElvitegravir Impurity 1Cat. No. P-E030-006CAS 949465-79-6
ImpurityElvitegravir Impurity 2Cat. No. P-E030-007CAS 697762-60-0
ImpurityL-ValinolCat. No. P-E030-008CAS 2026-48-4
Impuritypara-Hydroxy ElvitegravirCat. No. P-E030-009CAS 870648-10-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.