Active ingredientEnalaprilCat. No. P-E041-001CAS 75847-73-3
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Pharmacopoeial impurity · Enalapril family
Pharmaceutical analytical standardEnalapril EP Impurity A Maleate
- Cat. No.
- P-E041-006
- CAS
- 1356932-13-2
- Alternative CAS
- 76420-74-1 (free base)
- 77549-59-8 (alternative CAS, same compound)
- Formula
- C20H28N2O5·C4H4O4
- Molecular weight
- 492.52 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Enalapril
An ACE inhibitor for high blood pressure and heart failure, patented in 1978 and in use since the mid-1980s: it was created to improve on captopril, the first medicine of its class.
Did you know?The active molecule is actually enalaprilat, which is poorly absorbed by mouth: by turning it into an ethyl ester, researchers obtained a prodrug that the body converts back into the active form.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Enalapril family
Active ingredientEnalaprilCat. No. P-E041-001CAS 75847-73-3
Active ingredientEnalapril MaleateCat. No. P-E041-002CAS 76095-16-4
Pharmacopoeial impurityEnalapril Diketopiperazine Acid (R-Isomer)Cat. No. P-E041-003CAS 219677-80-2
Pharmacopoeial impurityEnalapril EP Impurity GCat. No. P-E041-004CAS 460720-14-3
Pharmacopoeial impurityEnalapril EP Impurity ACat. No. P-E041-005CAS 76420-74-1
Pharmacopoeial impurityEnalapril EP Impurity BCat. No. P-E041-007CAS 82717-96-2
Pharmacopoeial impurityEnalapril EP Impurity CCat. No. P-E041-008CAS 76420-72-9
Pharmacopoeial impurityEnalapril EP Impurity DCat. No. P-E041-009CAS 115729-52-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.