Pharmacopoeial impurityEnalaprilat EP Impurity ACat. No. P-E042-002
Drag to rotate
Active ingredient · Enalaprilat Dihydrate family
Pharmaceutical analytical standardEnalaprilat Dihydrate
Synonyms: NSC 760053, Enalaprilat
- Cat. No.
- P-E042-001
- CAS
- 84680-54-6
- Alternative CAS
- 76420-72-9 (anhydrous form)
- 2743427-06-5 (anhydrous form)
- Formula
- C18H24N2O5·2H2O
- Molecular weight
- 384.43 g/mol
- Category
- Active ingredient (API)
The active form of enalapril and the first ACE inhibitor with two carboxyl groups; since it is poorly absorbed by mouth, it is given intravenously to lower blood pressure.
Did you know?To make it absorbable by mouth, chemists esterified it with ethanol: the result was enalapril, a prodrug that the body's enzymes convert back into enalaprilat.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- EnalaprilatBP 742
- Enalaprilat dihydrate CRSEP Y0000615
- Enalaprilat for system suitability CRSEP Y0000629
More products in the Enalaprilat Dihydrate family
Pharmacopoeial impurityEnalaprilat EP Impurity ACat. No. P-E042-002
Pharmacopoeial impurityEnalaprilat EP Impurity A (R,R-Isomer)Cat. No. P-E042-003
Pharmacopoeial impurityEnalaprilat EP Impurity ECat. No. P-E042-004
MetaboliteEnalaprilat Acyl GlucuronideCat. No. P-E042-006
MetaboliteEnalaprilat N-GlucuronideCat. No. P-E042-007
NitrosamineN-Nitroso EnalaprilatCat. No. P-E042-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.