Pharmacopoeial impurityEnoxolone EP Impurity ACat. No. P-E051-002CAS 1449-05-4
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Active ingredient · Enoxolone family
Pharmaceutical analytical standardEnoxolone
Synonyms: Glycyrrhetinic Acid, Glycyrrhetic acid, Uralenic acid, Jintan, Rhetinic Acid, NSC 35347, Glyciram, Acid, Rhetinic, Acid, Uralenic, Acid, Glycyrrhetic, Acid, Glycyrrhetinic, Glycyram, Arthrodont, Glycyrrhetin, Glycyrrhetinate, alpha-Glycyrrhetinic acid, Enoloxone, NSC 35350, Hidermart
- Cat. No.
- P-E051-001
- CAS
- 471-53-4
- Alternative CAS
- 85985-61-1 (potassium salt)
- 2508-76-1 (sodium salt)
- 23327-65-3 (potassium salt)
- 7239-50-1 (ammonium salt)
- 107420-91-7 (alternative CAS, same compound)
- Formula
- C30H46O4
- Molecular weight
- 470.69 g/mol
- Category
- Active ingredient (API)
A triterpene also known as glycyrrhetinic acid, obtained from the glycyrrhizin of liquorice root: it is used in toothpastes, creams and pain-relief patches, and as a flavouring, because its sweet taste masks bitter ones.
Did you know?One of its metabolites slows, in the kidney, the conversion of cortisol into its inactive form: the excess cortisol retains sodium, which is why too much liquorice can raise blood pressure.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Enoxolone CRSEP E0180500
- Enoxolone for peak identification CRSEP Y0002340
More products in the Enoxolone family
Pharmacopoeial impurityEnoxolone EP Impurity ACat. No. P-E051-002CAS 1449-05-4
MetaboliteGlycyrrhetic Acid 3-O-beta-GlucuronideCat. No. P-E051-003CAS 400870-85-1
Impurity3-Oxoglycyrrhetinic acidCat. No. P-E051-004CAS 7020-50-0
ImpurityEnoxolone Impurity 1Cat. No. P-E051-005CAS 67951-04-6
ImpurityGlycyrrhizic AcidCat. No. P-E051-006CAS 1405-86-3
ImpurityIsoglycyrrhizinic acidCat. No. P-E051-007CAS 83896-44-0
ImpurityLicoricesaponin H2Cat. No. P-E051-008CAS 118441-85-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
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