Active ingredientEntecavirCat. No. P-E059-001CAS 142217-69-4
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Impurity or related compound · Entecavir family
Pharmaceutical analytical standardEntecavir Impurity 24
Synonyms: (1S,2R,3S,5R)-3-Phenylmethoxy-2-(phenylmethoxymethyl)-6-oxabicyclo[3.1.0]hexane
- Cat. No.
- P-E059-049
- CAS
- 110567-22-1
- Alternative CAS
- N/A
- Formula
- C20H22O3
- Molecular weight
- 310.39 g/mol
- Category
- Impurity or related compound
Family: Entecavir
A guanosine nucleoside analogue that blocks the replication of hepatitis B virus, approved in the United States in 2005 for the treatment of chronic hepatitis B.
Did you know?It was born in 1992 within a research programme against herpesviruses: only later was it found to be far more active against hepatitis B virus.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Entecavir family
Active ingredientEntecavirCat. No. P-E059-001CAS 142217-69-4
Active ingredientEntecavir MonohydrateCat. No. P-E059-003CAS 209216-23-9
IntermediateEntecavir Intermediate 5Cat. No. P-E059-004CAS 142217-78-5
Pharmacopoeial impurityEntecavir EP Impurity FCat. No. P-E059-005CAS 649761-24-0
Pharmacopoeial impurityEntecavir EP Impurity ACat. No. P-E059-006CAS 1367369-78-5
Pharmacopoeial impurityEntecavir EP Impurity BCat. No. P-E059-007CAS 1367369-77-4
Pharmacopoeial impurityEntecavir EP Impurity B HClCat. No. P-E059-008
Pharmacopoeial impurityEntecavir EP Impurity CCat. No. P-E059-009CAS 2204369-23-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.