MetaboliteErtugliflozin-3-O-beta-GlucuronideCat. No. P-E087-002CAS 1500090-85-6
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Active ingredient · Ertugliflozin family
Pharmaceutical analytical standardErtugliflozin
Synonyms: beta-L-Idopyranose, 1,6-anhydro-1-C-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-5-C-(hydroxymethyl)-, Steglatro
- Cat. No.
- P-E087-001
- CAS
- 1210344-57-2
- Alternative CAS
- 1210344-83-4 (other salt)
- Formula
- C22H25ClO7
- Molecular weight
- 436.88 g/mol
- Category
- Active ingredient (API)
An SGLT2 inhibitor (gliflozin) for type 2 diabetes, approved in the United States at the end of 2017: it makes the body pass some excess sugar in the urine by blocking its reabsorption in the kidneys.
Did you know?Its 'sugar' part is not a simple ring: an extra bridge locks it into a rigid bicyclic cage, unusual among gliflozins. It blocks SGLT2 more than 2000 times more strongly than SGLT1.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ertugliflozin family
MetaboliteErtugliflozin-3-O-beta-GlucuronideCat. No. P-E087-002CAS 1500090-85-6
Isotopically labelledErtugliflozin-d5Cat. No. P-E087-003CAS 1298086-22-2
Impurityent-ErtugliflozinCat. No. P-E087-004CAS 2242891-20-7
ImpurityErtugliflozin Hydroxy ImpurityCat. No. P-E087-005CAS 1298086-28-8
ImpurityErtugliflozin Hydroxy Impurity (R-Isomer)Cat. No. P-E087-006CAS 1298086-33-5
ImpurityErtugliflozin Hydroxy Impurity (S-Isomer)Cat. No. P-E087-007CAS 1298086-34-6
ImpurityErtugliflozin Impurity 19Cat. No. P-E087-008CAS 1298086-17-5
ImpurityErtugliflozin Impurity 1Cat. No. P-E087-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.