Active ingredientEthambutol diHClCat. No. P-E114-001CAS 1070-11-7
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Stable isotope labelled · Ethambutol family
Pharmaceutical analytical standardEthambutol-d8
- Cat. No.
- P-E114-007
- CAS
- 1129526-23-3
- Alternative CAS
- 1070-11-7 (unlabelled form, dihydrochloride)
- Formula
- C10H16D8N2O2
- Molecular weight
- 212.36 g/mol
- Category
- Stable isotope labelled
Family: Ethambutol
An antituberculosis drug discovered in 1961 that hinders the building of the mycobacterial cell wall by blocking the enzyme arabinosyl transferase; it is used with isoniazid, rifampicin and pyrazinamide and is on the WHO List of Essential Medicines.
Did you know?It is a classic example of an 'old' drug introduced as a single enantiomer from the start: the (S,S) form is 500 times more potent than its (R,R) mirror image and 12 times more than the meso form.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ethambutol family
Active ingredientEthambutol diHClCat. No. P-E114-001CAS 1070-11-7
Pharmacopoeial impurityEthambutol EP Impurity BCat. No. P-E114-002
Pharmacopoeial impurityEthambutol EP Impurity B DihydrochlorideCat. No. P-E114-003CAS 32454-69-6
Pharmacopoeial impurityEthambutol EP Impurity CCat. No. P-E114-004CAS 134566-79-3
Isotopically labelled(R,R)-Ethambutol-d4 DiHClCat. No. P-E114-005
Isotopically labelledEthambutol-d4Cat. No. P-E114-006CAS 1129526-19-7
NitrosamineN,N-Dinitroso EthambutolCat. No. P-E114-008CAS 2792161-95-4
NitrosamineN-Nitroso EthambutolCat. No. P-E114-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.