Active ingredientEtoposideCat. No. P-E139-001CAS 33419-42-0
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Pharmacopoeial impurity · Etoposide family
Pharmaceutical analytical standardEtoposide EP Impurity O
Synonyms: 2,3-Bis-O-(Dichloroacetyl) Etoposide
- Cat. No.
- P-E139-016
- CAS
- N/A
- Alternative CAS
- 260974-95-6 (alternative CAS, same compound)
- Formula
- C33H32Cl4O15
- Molecular weight
- 810.40 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Etoposide
An anticancer drug that blocks topoisomerase II, a semi-synthetic derivative of podophyllotoxin: first synthesised in 1966 and approved in the United States in 1983, it is used for testicular and lung cancers.
Did you know?The parent compound podophyllotoxin is extracted from the rhizome of the mayapple, Podophyllum peltatum, a North American woodland plant also called American mandrake.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Etoposide family
Active ingredientEtoposideCat. No. P-E139-001CAS 33419-42-0
Active ingredientEtoposide PhosphateCat. No. P-E139-002CAS 117091-64-2
Pharmacopoeial impurityEtoposide EP Impurity ACat. No. P-E139-003CAS 124151-67-3
Pharmacopoeial impurityEtoposide EP Impurity BCat. No. P-E139-004CAS 100007-56-5
Pharmacopoeial impurityEtoposide EP Impurity CCat. No. P-E139-005CAS 100007-53-2
Pharmacopoeial impurityEtoposide EP Impurity DCat. No. P-E139-006CAS 23363-35-1
Pharmacopoeial impurityEtoposide EP Impurity ECat. No. P-E139-007CAS 6559-91-7
Pharmacopoeial impurityEtoposide EP Impurity FCat. No. P-E139-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.