Active ingredientFebuxostatCat. No. P-F011-001CAS 144060-53-7
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Impurity or related compound · Febuxostat family
Pharmaceutical analytical standardFebuxostat Impurity 21
Synonyms: Ethyl 2-[4-hydroxy-3-[(E)-hydroxyiminomethyl]phenyl]-4-methyl-1,3-thiazole-5-carboxylate
- Cat. No.
- P-F011-062
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C14H14N2O4S
- Molecular weight
- 306.34 g/mol
- Category
- Impurity or related compound
Family: Febuxostat
A xanthine oxidase inhibitor, blocking the enzyme that produces uric acid: discovered in Japan, it was approved in the US in 2009 for the long-term treatment of hyperuricaemia in people with gout.
Did you know?At its US debut it was presented as the first new treatment option in more than 40 years for gout-related hyperuricaemia.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Febuxostat family
Active ingredientFebuxostatCat. No. P-F011-001CAS 144060-53-7
MetaboliteFebuxostat Acyl GlucuronideCat. No. P-F011-002CAS 1351692-92-6
MetaboliteFebuxostat Acyl-a-D-GlucuronideCat. No. P-F011-003
MetaboliteFebuxostat Metabolite 1Cat. No. P-F011-004CAS 887945-96-2
MetaboliteFebuxostat Metabolite 2Cat. No. P-F011-005CAS 407582-47-2
MetaboliteFebuxostat Metabolite 3Cat. No. P-F011-006CAS 407582-49-4
Isotopically labelledFebuxostat-d7Cat. No. P-F011-007CAS 1285539-74-3
Isotopically labelledFebuxostat-d9Cat. No. P-F011-008CAS 1246819-50-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.