Isotopically labelledFilgotinib-d4Cat. No. P-F044-002CAS 2041095-50-3
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Active ingredient · Filgotinib family
Pharmaceutical analytical standardFilgotinib
Synonyms: N-(5-(4-((1,1-dioxo-1,4-thiazinan-4-yl)methyl)phenyl)-(1,2,4)triazolo(1,5-a)pyridin-2-yl)cyclopropanecarboxamide, N-(5-(4-((1,1-dioxo-1lambda6-thiomorpholin-4-yl)methyl)phenyl)-(1,2,4)triazolo(1,5-a)pyridin-2-yl)cyclopropanecarboxamide, Jyseleca, NSC 800100, Cyclopropanecarboxamide, n-(5-(4-((1,1-dioxido-4-thiomorpholinyl)methyl)phenyl)(1,2,4)triazolo(1,5-a)pyridin-2-yl)-
- Cat. No.
- P-F044-001
- CAS
- 1206161-97-8
- Alternative CAS
- 1802998-75-9 (maleate)
- 1540859-07-1 (hydrochloride hydrate)
- 1206101-20-3 (alternative CAS, same compound)
- Formula
- C21H23N5O3S
- Molecular weight
- 425.51 g/mol
- Category
- Active ingredient (API)
A Janus kinase inhibitor with a preference for JAK1, taken by mouth: approved in September 2020 in the European Union and Japan for moderate to severe active rheumatoid arthritis in adults.
Did you know?It was developed by a Belgian-Dutch biotech company and, curiously, it is not broken down by the liver's cytochrome P450 enzymes but by carboxylesterases.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Filgotinib family
Isotopically labelledFilgotinib-d4Cat. No. P-F044-002CAS 2041095-50-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.