Active ingredientFlucloxacillin SodiumCat. No. P-F068-001CAS 1847-24-1
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Pharmacopoeial impurity · Flucloxacillin family
Pharmaceutical analytical standardFlucloxacillin EP Impurity D
Synonyms: 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid, 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid, Fcimic acid
- Cat. No.
- P-F068-004
- CAS
- 3919-74-2
- Alternative CAS
- 83817-49-6 (potassium salt)
- Formula
- C11H7ClFNO3
- Molecular weight
- 255.63 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Flucloxacillin
A penicillinase-resistant penicillin of the isoxazolyl penicillin family, patented in England in 1961 and in use since the 1970s, mainly against staphylococcal infections.
Did you know?Compared with cloxacillin it has just one extra fluorine atom, hence its name; in activity and uses it is considered interchangeable with its 'cousin' dicloxacillin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Flucloxacillin impurity D CRSEP Y0000890
More products in the Flucloxacillin family
Active ingredientFlucloxacillin SodiumCat. No. P-F068-001CAS 1847-24-1
Pharmacopoeial impurityFlucloxacillin EP Impurity ACat. No. P-F068-002CAS 42947-70-6
Pharmacopoeial impurityFlucloxacillin EP Impurity B (Mixture of Diastereomers)Cat. No. P-F068-003CAS 1276016-89-7
Pharmacopoeial impurityFlucloxacillin EP Impurity ECat. No. P-F068-005CAS 2924817-37-6
Pharmacopoeial impurityFlucloxacillin Sodium EP Impurity A (as Disodium Salt)Cat. No. P-F068-006CAS 68728-50-7
Impurity5-Hydroxymethyl FlucloxacillinCat. No. P-F068-007CAS 75524-31-1
ImpurityFlucloxacillin Impurity 1 Disodium SaltCat. No. P-F068-009
ImpurityFlucloxacillin Impurity 2Cat. No. P-F068-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.