Active ingredientFluconazoleCat. No. P-F069-001CAS 86386-73-4
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Pharmacopoeial impurity · Fluconazole family
Pharmaceutical analytical standardFluconazole EP Impurity D
Synonyms: 2-(4-Fluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol, 2-(4-fluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol, alpha-(4-Fluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol, alpha-(4-Fluorophenyl)-alpha-(triazol-1-ylmethyl)-as-triazoleethanol, Fluconazole impurity D, Fluconazole impurity d (ep impurity), Fluconazole EP Impurity D/ Fluconazole Related Compound B (2-Desfluoro Fluconazole), Fluconazole Impurity 15
- Cat. No.
- P-F069-005
- CAS
- 81886-51-3
- Alternative CAS
- N/A
- Formula
- C13H13FN6O
- Molecular weight
- 288.29 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Fluconazole
A triazole antifungal patented in the United Kingdom in 1981 and on the market since 1988, used against candidiasis and cryptococcosis. It is on the World Health Organization's List of Essential Medicines.
Did you know?It was born in Sandwich, Kent: of the four most potent triazoles studied, only the one with a 2,4-difluorophenyl group was water-soluble, so it could also be given intravenously.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Fluconazole family
Active ingredientFluconazoleCat. No. P-F069-001CAS 86386-73-4
Pharmacopoeial impurityFluconazole EP Impurity ACat. No. P-F069-002CAS 89429-59-4
Pharmacopoeial impurityFluconazole EP Impurity BCat. No. P-F069-003CAS 871550-15-1
Pharmacopoeial impurityFluconazole EP Impurity CCat. No. P-F069-004CAS 514222-44-7
Pharmacopoeial impurityFluconazole EP Impurity FCat. No. P-F069-006CAS 118689-07-9
Pharmacopoeial impurityFluconazole EP Impurity GCat. No. P-F069-007CAS 86386-76-7
Pharmacopoeial impurityFluconazole EP Impurity G MesylateCat. No. P-F069-008CAS 86386-77-8
Pharmacopoeial impurityFluconazole EP Impurity HCat. No. P-F069-009CAS 150194-52-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.