Active ingredientFluticasoneCat. No. P-F104-001CAS 90566-53-3
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Active ingredient · Fluticasone family
Pharmaceutical analytical standardFluticasone Propionate
Synonyms: Flovent, Cutivate, Flixotide, Flonase, Flovent HFA, Flovent Diskus, Xhance, ArmonAir RespiClick, Flonase Allergy Relief, Nasofan, Pirinase, Sereflo, Sirdupla, Childrens nasal, FlutiCare, Aerivio Spiromax, Childrens Nasopro, Airflusal forspiro, Allergy relief nasal, Childrens allergy nasal, Walgreens allergy nasal, Childrens flonase, Armonair digihaler, Leader allergy relief nasal, Kirkland Signature Aller Flo, Topcare Allergy Relief Nasal, Basic care allergy relief nasal, DG Health Allergy Relief Nasal, Caring mill allergy relief nasal, Harris Teeter Allergy Relief Nasal, Childrens flonase allergy relief, Basic care childrens allergy relief nasal, DG Health childrens allergy relief nasal, Caring mill childrens allergy relief nasal, Flixonase, Flutide, Flusonal, Fluspiral, Flutivate, Asmatil, Axotide, Brethal, Fluinol, Flixotide Disks, Flixotide Disk, Flixotide Inhaler, Cultivate, Fluticasonpropionat Allen, Atemur, Inalacor, Rinosone, Trialona, Ubizol, Zoflut, Flonase Aq, Skyron, Fluxonal, Flovent Rotadisk, ArmonAir RespiClickTM, S-(Fluoromethyl) 6alpha,9-difluoro-11beta,17-dihydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carbothioate, 17-propionate, s-fluoromethyl 6alpha, 9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17.beta-. carbothioate
- Cat. No.
- P-F104-003
- CAS
- 80474-14-2
- Alternative CAS
- N/A
- Formula
- C25H31F3O5S
- Molecular weight
- 500.57 g/mol
- Category
- Active ingredient (API)
Family: Fluticasone
A synthetic fluorine-containing corticosteroid, patented in 1980 and approved for medical use in 1990: it is inhaled for asthma and COPD and used as a nasal spray for allergic rhinitis.
Did you know?What is swallowed is poorly absorbed and almost entirely broken down by the gut and liver before reaching the circulation: taken by mouth, its bioavailability is below 1%.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Fluticasone PropionateBP 587
- Fluticasone propionate CRSEP Y0000284
More products in the Fluticasone family
Active ingredientFluticasoneCat. No. P-F104-001CAS 90566-53-3
Active ingredientFluticasone FuroateCat. No. P-F104-002CAS 397864-44-7
Pharmacopoeial impurityFluticasone Furoate EP Impurity ACat. No. P-F104-004CAS 397864-63-0
Pharmacopoeial impurityFluticasone Furoate EP Impurity ECat. No. P-F104-005CAS 398454-97-2
Pharmacopoeial impurityFluticasone Furoate EP Impurity FCat. No. P-F104-006
Pharmacopoeial impurityFluticasone Furoate EP Impurity GCat. No. P-F104-007CAS 785806-96-4
Pharmacopoeial impurityFluticasone Furoate EP Impurity HCat. No. P-F104-008
Pharmacopoeial impurityFluticasone Furoate EP Impurity ICat. No. P-F104-009CAS 3086156-07-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.