Active ingredientFosinopril sodium saltCat. No. P-F122-001CAS 88889-14-9
Drag to rotate
Pharmacopoeial impurity · Fosinopril family
Pharmaceutical analytical standardFosinopril EP Impurity I
Synonyms: Acetic acid, 2-((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)-
- Cat. No.
- P-F122-005
- CAS
- 123599-82-6
- Alternative CAS
- 123599-78-0 (alternative CAS, same compound)
- Formula
- C19H29O6P
- Molecular weight
- 384.41 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Fosinopril
An ACE inhibitor used for hypertension and heart failure, patented in 1980 and approved in 1991: it is a prodrug that the liver and gut lining convert into the active form, fosinoprilat.
Did you know?It is the only marketed ACE inhibitor that contains phosphorus and, unlike most of its relatives, it is eliminated by both the kidneys and the liver.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Fosinopril impurity I CRSEP Y0001232
More products in the Fosinopril family
Active ingredientFosinopril sodium saltCat. No. P-F122-001CAS 88889-14-9
Pharmacopoeial impurityFosinopril EP Impurity BCat. No. P-F122-002
Pharmacopoeial impurityFosinopril EP Impurity CCat. No. P-F122-003
Pharmacopoeial impurityFosinopril EP Impurity DCat. No. P-F122-004CAS 1356446-78-0
Pharmacopoeial impurityFosinopril EP Impurity KCat. No. P-F122-006
Pharmacopoeial impurityFosinopril EP Impurity ECat. No. P-F122-007
Pharmacopoeial impurityFosinopril EP Impurity NCat. No. P-F122-008
Pharmacopoeial impurityFosinoprilatCat. No. P-F122-009CAS 95399-71-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.