Active ingredientFosravuconazole Disodium SaltCat. No. P-F123-001CAS 351227-62-8
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Impurity or related compound · Fosravuconazole family
Pharmaceutical analytical standardFosravuconazole Impurity 1
Synonyms: 4-[2-[(1R)-1-[(4R)-4-(2,4-Difluorophenyl)-1,3-dioxolan-4-yl]ethyl]-1,3-thiazol-4-yl]benzonitrile
- Cat. No.
- P-F123-003
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C21H16F2N2O2S
- Molecular weight
- 398.43 g/mol
- Category
- Impurity or related compound
Family: Fosravuconazole
An oral triazole antifungal, a prodrug the body converts into ravuconazole: it was approved in Japan in 2018 to treat onychomycosis, the fungal infection of the nails.
Did you know?From nail drug to hope for a neglected disease: in a phase II trial run with the non-profit DNDi it proved effective against eumycetoma, which mainly affects young adults in poor rural areas.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Fosravuconazole family
Active ingredientFosravuconazole Disodium SaltCat. No. P-F123-001CAS 351227-62-8
ImpurityFosravuconazole Amide ImpurityCat. No. P-F123-002CAS 942415-34-1
ImpurityFosravuconazole Impurity 2Cat. No. P-F123-004
ImpurityFosravuconazole L-Lysine EthanolateCat. No. P-F123-005CAS 914361-45-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.