Active ingredientGadobutrolCat. No. P-G003-001CAS 770691-21-9
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Impurity or related compound · Gadobutrol family
Pharmaceutical analytical standardGadobutrol Impurity 28
Synonyms: 1-(2-Bromoethyl)-1,4,7,10-tetrazacyclododecane
- Cat. No.
- P-G003-046
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C10H23BrN4
- Molecular weight
- 279.23 g/mol
- Category
- Impurity or related compound
Family: Gadobutrol
A macrocyclic gadolinium-based contrast agent for magnetic resonance imaging, used to highlight lesions of the nervous system, breast and blood vessels; approved in Switzerland in 1998 and in the United States in 2011.
Did you know?It is formulated at a 1 molar concentration, higher than that of other gadolinium contrast agents: the same dose needs a smaller volume of liquid.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Gadobutrol family
Active ingredientGadobutrolCat. No. P-G003-001CAS 770691-21-9
Active ingredientGadobutrol monohydrateCat. No. P-G003-002CAS 198637-52-4
NitrosamineN-Nitroso Gadobutrol Impurity 1 DitrifluoroacetateCat. No. P-G003-003
NitrosamineN-Nitroso Gadobutrol Impurity 2Cat. No. P-G003-004
NitrosamineN-Nitroso Gadobutrol Impurity 3Cat. No. P-G003-005
NitrosamineN-Nitroso Gadobutrol Impurity 4Cat. No. P-G003-006
NitrosamineN-Nitroso Gadobutrol Impurity 5Cat. No. P-G003-007
NitrosamineN-Nitroso Gadobutrol Impurity 6Cat. No. P-G003-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.