Isotopically labelledGepirone-d8Cat. No. P-G029-002CAS 2749331-28-8
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Active ingredient · Gepirone family
Pharmaceutical analytical standardGepirone
Synonyms: Ariza, Variza, Gepiron ER
- Cat. No.
- P-G029-001
- CAS
- 83928-76-1
- Alternative CAS
- 83928-66-9 (hydrochloride)
- 108964-56-3 (other form)
- Formula
- C19H29N5O2
- Molecular weight
- 359.47 g/mol
- Category
- Active ingredient (API)
An antidepressant of the azapirone family, related to buspirone, that acts as a selective partial agonist of the serotonin 5-HT1A receptor; it was approved in the United States in September 2023 for major depressive disorder in adults.
Did you know?It took almost forty years to reach patients: synthesised in 1986, it received several negative reviews before its approval in 2023.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Gepirone family
Isotopically labelledGepirone-d8Cat. No. P-G029-002CAS 2749331-28-8
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Impurity3-Hydroxy GepironeCat. No. P-G029-004CAS 345894-78-2
ImpurityGepirone Impurity 1Cat. No. P-G029-005CAS 1634669-41-2
ImpurityGepirone Impurity 2Cat. No. P-G029-006CAS 152555-27-6
ImpurityGepirone Impurity 3Cat. No. P-G029-007CAS 116732-70-8
ImpurityGepirone Impurity 4Cat. No. P-G029-008CAS 345894-79-3
ImpurityGepirone Impurity 5Cat. No. P-G029-009CAS 138274-09-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.