Active ingredientGilteritinibCat. No. P-G032-001CAS 1254053-43-4
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Active ingredient · Gilteritinib family
Pharmaceutical analytical standardGilteritinib Hemifumarate
Synonyms: Gilteritinib Fumarate, Xospata
- Cat. No.
- P-G032-002
- CAS
- 1254053-84-3
- Alternative CAS
- 1254053-43-4 (free base)
- Formula
- C62H92N16O10
- Molecular weight
- 1221.52 g/mol
- Category
- Active ingredient (API)
Family: Gilteritinib
An oral FLT3 kinase inhibitor, approved in the United States in November 2018 for adults with relapsed or refractory acute myeloid leukaemia carrying a mutation of the FLT3 gene.
Did you know?Alongside the drug, the FDA extended the use of a diagnostic test that detects the FLT3 mutation: the treatment is intended only for patients in whom the test finds it.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Gilteritinib family
Active ingredientGilteritinibCat. No. P-G032-001CAS 1254053-43-4
Isotopically labelledGilteritinib-d8Cat. No. P-G032-003CAS 2377109-74-3
ImpurityGilteritinib Impurity 1Cat. No. P-G032-004CAS 1254058-34-8
ImpurityGilteritinib Impurity 2Cat. No. P-G032-005
ImpurityGilteritinib Impurity 3Cat. No. P-G032-006CAS 2043019-99-2
ImpurityGilteritinib Impurity 4Cat. No. P-G032-007CAS 1373410-40-2
ImpurityGilteritinib N-Methyl N-Oxide ImpurityCat. No. P-G032-008
ImpurityGilteritinib N-Oxide ImpurityCat. No. P-G032-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.