Active ingredientGlibenclamideCat. No. P-G038-001CAS 10238-21-8
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Stable isotope labelled · Glibenclamide family
Pharmaceutical analytical standardGlyburide-d3
- Cat. No.
- P-G038-007
- CAS
- 1219803-02-7
- Alternative CAS
- 10238-21-8 (unlabelled form)
- 23047-14-5 (unlabelled form, potassium salt)
- 52169-36-5 (unlabelled form, potassium salt)
- Formula
- C23H25ClN3O5SD3
- Molecular weight
- 497.02 g/mol
- Category
- Stable isotope labelled
Family: Glibenclamide
A second-generation sulfonylurea that prompts the pancreas to release insulin, developed in Germany in the late 1960s for type 2 diabetes; in the United States it is known as glyburide.
Did you know?After a stroke the damaged blood-brain barrier lets it reach the brain, where it binds mainly to the affected hemisphere: this is why it is also being studied in neurology.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Glibenclamide family
Active ingredientGlibenclamideCat. No. P-G038-001CAS 10238-21-8
Pharmacopoeial impurityGlibenclamide EP Impurity ACat. No. P-G038-002CAS 16673-34-0
Pharmacopoeial impurityGlibenclamide EP Impurity BCat. No. P-G038-003CAS 21165-77-5
Pharmacopoeial impurityGlibenclamide EP Impurity DCat. No. P-G038-004CAS 38160-73-5
Pharmacopoeial impurityGlibenclamide EP Impurity ECat. No. P-G038-005CAS 57334-89-1
Isotopically labelledGlyburide-d11Cat. No. P-G038-006CAS 1189985-02-1
Isotopically labelledrac-cis-3-Hydroxy-Glyburide-13C-d3Cat. No. P-G038-008CAS 1217848-91-3
Isotopically labelledrac-trans-3-Hydroxy-Glyburide-13C-d3Cat. No. P-G038-009CAS 1217639-30-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.