Active ingredientHalometasoneCat. No. P-H005-001CAS 50629-82-8
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Impurity or related compound · Halometasone family
Pharmaceutical analytical standardHalometasone Impurity 9
Synonyms: (6S,8S,9R,10S,11S,13S,14S,16R,17R)-2-Chloro-17-[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-2-chloro-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-2-yl]-2-hydroxyacetyl]-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- Cat. No.
- P-H005-014
- CAS
- 136154-83-1
- Alternative CAS
- N/A
- Formula
- C44H54Cl2F4O10
- Molecular weight
- 889.80 g/mol
- Category
- Impurity or related compound
Family: Halometasone
A potent synthetic topical corticosteroid, approved in many European countries, including Switzerland, Germany and Spain, and in Asia; it is used as a cream for chronic psoriasis and acute non-infected eczema.
Did you know?It is one of the tri-halogenated corticosteroids: its molecule contains three halogen atoms, one chlorine and two fluorines, attached to the steroid skeleton.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Halometasone family
Active ingredientHalometasoneCat. No. P-H005-001CAS 50629-82-8
Active ingredientHalometasone MonohydrateCat. No. P-H005-002CAS 1310709-74-0
Impurity17-Keto HalometasoneCat. No. P-H005-003CAS 136132-00-8
ImpurityHalometasone 17-carboxylic acidCat. No. P-H005-004CAS 80157-55-7
ImpurityHalometasone Impurity 1Cat. No. P-H005-005
ImpurityHalometasone Impurity 2Cat. No. P-H005-006CAS 23961-24-2
ImpurityHalometasone Impurity 3Cat. No. P-H005-007
ImpurityHalometasone Impurity 4Cat. No. P-H005-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.