Active ingredientHyoscine ButylbromideCat. No. P-H053-001CAS 149-64-4
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Pharmacopoeial impurity · Hyoscine Butylbromide family
Pharmaceutical analytical standardHyoscine Butylbromide EP Impurity E
- Cat. No.
- P-H053-003
- CAS
- 14861-14-4
- Alternative CAS
- 22235-98-9 (hydrochloride)
- Formula
- C20H27NO4
- Molecular weight
- 345.44 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Hyoscine Butylbromide
A semi-synthetic antispasmodic derived from hyoscine (scopolamine), an alkaloid of plants of the nightshade family such as deadly nightshade; patented in 1950 and approved in 1951, it is used for painful cramps and spasms of the stomach, intestine and urinary tract.
Did you know?Adding the butyl bromide group prevents it from crossing the blood-brain barrier: so it acts on the abdominal muscles with few effects on the brain, unlike scopolamine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Hyoscine Butylbromide family
Active ingredientHyoscine ButylbromideCat. No. P-H053-001CAS 149-64-4
Pharmacopoeial impurityHyoscine Butylbromide EP Impurity D Bromide (Mixture of Diastereomers)Cat. No. P-H053-002
Pharmacopoeial impurityHyoscine Butylbromide EP Impurity E HClCat. No. P-H053-004CAS 22235-98-9
Pharmacopoeial impurityHyoscine Butylbromide EP Impurity F BromideCat. No. P-H053-005CAS 150521-10-1
Pharmacopoeial impurityHyoscine Butylbromide EP Impurity GCat. No. P-H053-006CAS 92714-23-3
Pharmacopoeial impurityHyoscine Butylbromide EP Impurity HCat. No. P-H053-007
Pharmacopoeial impurityHyoscine Butylbromide EP Impurity H ChlorideCat. No. P-H053-008
Pharmacopoeial impurityrac-Hyoscine Butylbromide EP Impurity E HClCat. No. P-H053-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.