Active ingredientIdarubicinCat. No. P-I015-001CAS 58957-92-9
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Impurity or related compound · Idarubicin family
Pharmaceutical analytical standardIdarubicin Impurity 1
Synonyms: 2-Acetyl-6,7,11-trihydroxytetracene-5,12-dione, 8-Acetyl-1,6,11-trihydroxytetracene-5,12-dione
- Cat. No.
- P-I015-006
- CAS
- 78901-92-5
- Alternative CAS
- N/A
- Formula
- C20H12O6
- Molecular weight
- 348.31 g/mol
- Category
- Impurity or related compound
Family: Idarubicin
An anthracycline obtained in Italy in the mid-1970s by modifying daunorubicin, hence its chemical name 4-demethoxydaunorubicin; approved in the United States in 1990, it is used mainly in acute myeloid leukaemia.
Did you know?Compared with daunorubicin it lacks just one methoxy group: this small change makes it an anthracycline that works even when taken by mouth.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Idarubicin family
Active ingredientIdarubicinCat. No. P-I015-001CAS 58957-92-9
Active ingredientIdarubicin HydrochlorideCat. No. P-I015-002CAS 57852-57-0
Isotopically labelledIdarubicin-13C-d3Cat. No. P-I015-003
Isotopically labelledIdarubicin-d4Cat. No. P-I015-004
Impurity2,6,11-Trihydroxytetracene-5,12-dioneCat. No. P-I015-005CAS 66314-42-9
ImpurityDehydroxy IdarubicinCat. No. P-I015-007
ImpurityDianhydro IdarubicinaglyconeCat. No. P-I015-008CAS 84499-12-7
ImpurityIdarubicin Impurity 2Cat. No. P-I015-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.