Pharmacopoeial impurityIsoniazid EP Impurity BCat. No. P-I089-002CAS 1453-82-3
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Active ingredient · Isoniazid family
Pharmaceutical analytical standardIsoniazid
Synonyms: pyridine-4-carbohydrazide, Isonicotinic acid hydrazide, Isonicotinohydrazide, Rimifon, Nydrazid, Cotinazin, Dinacrin, Hydrazid, Iscotin, Mybasan, Cedin, Hidrasonil, Isonicotan, Nicotibina, Armazide, Ditubin, Ertuban, Isidrina, Isobicina, Laniazid, Neumandin, Hyzyd, Atcotibine, Isonidrin, Isotebezid, Stanozide, Armazid, Eralon, Isolyn, Isonex, Isonico, Isozide, Neoteben, Niadrin, Nicetal, Nicizina, Niconyl, Nicozide, Nikozid, Nyscozid, Pelazid, Pycazide, Rimitsid, Andrazide, Diforin, Eutizon, Hidrulta, Hycozid, Ismazide, Isocotin, Isonicid, Isonilex, Isonindon, Isonizide, Nidaton, Nidrazid, Tubazide, Isocid, Isonicotinylhydrazine, Isozyd, Neoxin, Niplen, Nevin, Inah, Ido-tebin, Isonicotinic hydrazide, Isohydrazide, Isonicotinhydrazid, Antimicina, Chemiazid, Chemidon, Fimalene, Hidranizil, Isocidene, Isonerit, Isonicotil, Isonikazid, Isonirit, Isoniton, Pyricidin, Pyrizidin, Raumanon, Retozide, Teebaconin, Azuren, Cemidon, Defonin, Ebidene, Evalon, Hidrun, Idrazil, Inizid, Isonide, Isonin, Nitadon, Rimicid, Tubazid, Antituberkulosum, Cotinizin, Isonicazide, Nicotibine, Nicotisan, Rimiphone, Tisiodrazida, Tubilysin, Isotebe, Isotinyl, Nicazide, Phthisen, Pyreazid, Percin, Razide, Tyvid, Neo-Tizide, Preparation 6424, Armacide, Cortinazine, GINK, Isotamine, Robisellin, Sauterazid, Tibinide, Unicozyde, Vazadrine, Zonazide, Isonicotinyl hydrazide, Tebecid, Tekazin, Tubeco, Tubicon, Tubomel, Vederon, Zinadon, Isonicotinoyl hydrazide, TB-Razide, Sanohidrazina, Robiselin, Tibizide, Tuberian, Niteban, Roxifen, Tebenic, Tebexin, Tebilon, Tibison, Tibivis, Tibusan, Tizide, Tebos, Tisin, TB-Vis, TB-Phlogin, Isozid, Isonicotinoylhydrazine, Cedin (Aerosol), Bacillen, Tebemid, Tubercid, Isonizida, Dianicotyl, Ipcazide, Isonicotinsaeurehydrazid, NSC 9659, Hydrazide, Isonicotinic Acid, Acid Vanillylidenehydrazide, Isonicotinic, Vanillylidenehydrazide, Isonicotinic Acid, Niazid, Isoniacid, Dibutin, Hyozid, Laniozid, Pyridicin, Sauterzid, Tibazide, Unicocyde, Inh-Burgthal, Zidafimia, Isokin, Tubizid, Hydra, Continazine, Tubecotubercid, Abdizide, Anidrasona, Tibemid, Tibiazide, Fetefu, Lanizid, Usaf cb-2, Lsoniazid, Mayambutol, Isotiny, Idrazide dell'acido isonicotinico, Isonicotinhydrazide, Isonicotinate hydrazide, Isonicotinic acid hydrazid, Isonicotinic acid hydrazone
- Cat. No.
- P-I089-001
- CAS
- 54-85-3
- Alternative CAS
- 1123-87-1 (dihydrochloride)
- Formula
- C6H7N3O
- Molecular weight
- 137.14 g/mol
- Category
- Active ingredient (API)
An antibiotic specific for tuberculosis, synthesised in Prague in 1912 by Hans Meyer and Josef Mally but used against tuberculosis only from the early 1950s; it is on the WHO List of Essential Medicines.
Did you know?After its synthesis it sat forgotten for decades. Together with its relative iproniazid, it was also among the first drugs to be called antidepressants.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- IsoniazidBP 1083
- Isoniazid CRSEP I0500000
More products in the Isoniazid family
Pharmacopoeial impurityIsoniazid EP Impurity BCat. No. P-I089-002CAS 1453-82-3
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Impurity2,5-Bis(4-pyridyl)-1,3,4-oxadiazoleCat. No. P-I089-004CAS 15420-02-7
Impurity2-IsoniazidCat. No. P-I089-005CAS 1452-63-7
ImpurityIsoniazid Ethylene DimerCat. No. P-I089-006CAS 27853-51-6
ImpurityIsoniazid Impurity 1Cat. No. P-I089-007CAS 4813-04-1
ImpurityN'-Methylidenepyridine-4-carbohydrazideCat. No. P-I089-008CAS 4813-02-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.