Active ingredientJosamycinCat. No. P-J002-001CAS 16846-24-5
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Pharmacopoeial impurity · Josamycin family
Pharmaceutical analytical standardJosamycin EP Impurity E
Synonyms: Platenomycin A1, Leucomycin V, 4(B)-(3-methylbutanoate) 3-propanoate
- Cat. No.
- P-J002-007
- CAS
- 40615-47-2
- Alternative CAS
- N/A
- Formula
- C43H71NO15
- Molecular weight
- 842.03 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Josamycin
A macrolide antibiotic with a 16-membered ring, produced by the soil bacterium Streptomyces narbonensis var. josamyceticus and isolated in 1964: it is used for respiratory, oral and skin infections.
Did you know?It was isolated by the team of the Japanese scientist Hamao Umezawa, one of the great antibiotic hunters of the 20th century, who also gave us kanamycin and the anticancer drug bleomycin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Josamycin family
Active ingredientJosamycinCat. No. P-J002-001CAS 16846-24-5
Pharmacopoeial impurityJosamycin EP Impurity ACat. No. P-J002-003CAS 18361-46-1
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Pharmacopoeial impurityJosamycin EP Impurity CCat. No. P-J002-005
Pharmacopoeial impurityJosamycin EP Impurity DCat. No. P-J002-006CAS 22340-94-9
Pharmacopoeial impurityJosamycin EP Impurity FCat. No. P-J002-008CAS 22875-15-6
Pharmacopoeial impurityJosamycin EP Impurity GCat. No. P-J002-009CAS 18361-49-4
Pharmacopoeial impurityJosamycin EP Impurity HCat. No. P-J002-010CAS 16846-34-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.