Active ingredientLamivudineCat. No. P-L009-001CAS 134678-17-4
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Impurity or related compound · Lamivudine family
Pharmaceutical analytical standardLamivudine Impurity 5
Synonyms: 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-3,3-dioxo-1,3-oxathiolan-5-yl]pyrimidin-2-one
- Cat. No.
- P-L009-028
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C8H11N3O5S
- Molecular weight
- 261.25 g/mol
- Category
- Impurity or related compound
Family: Lamivudine
A nucleoside reverse transcriptase inhibitor, also known as 3TC, approved in the United States in 1995: it is used against HIV, in combination with other antiretrovirals, and against chronic hepatitis B.
Did you know?It was created between 1988 and 1989 in Montreal, Canada, through the work of Bernard Belleau and Paul Nguyen-Ba; the code 3TC recalls its chemical name 3'-thiacytidine, because a sulphur atom sits in the sugar ring.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Lamivudine family
Active ingredientLamivudineCat. No. P-L009-001CAS 134678-17-4
Pharmacopoeial impurityLamivudine AcidCat. No. P-L009-002CAS 173829-09-9
Pharmacopoeial impurityLamivudine EP Impurity ACat. No. P-L009-003CAS 173602-25-0
Pharmacopoeial impurityLamivudine EP Impurity BCat. No. P-L009-005CAS 136846-20-3
Pharmacopoeial impurityLamivudine EP Impurity D (Lamivudine Enantiomer)Cat. No. P-L009-006CAS 134680-32-3
Pharmacopoeial impurityLamivudine EP Impurity ECat. No. P-L009-007CAS 71-30-7
Pharmacopoeial impurityLamivudine EP Impurity GCat. No. P-L009-008CAS 160552-55-6
Pharmacopoeial impurityLamivudine EP Impurity HCat. No. P-L009-009CAS 160552-54-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.