Active ingredientLaquinimodCat. No. P-L018-001CAS 248281-84-7
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Active ingredient · Laquinimod family
Pharmaceutical analytical standardLaquinimod Sodium Salt
Synonyms: Nerventra, SAIK-MS compound
- Cat. No.
- P-L018-002
- CAS
- 248282-07-7
- Alternative CAS
- 248281-84-7 (free acid)
- 1354744-14-1 (alternative CAS, same compound)
- Formula
- C19H16ClN2NaO3
- Molecular weight
- 378.79 g/mol
- Category
- Active ingredient (API)
Family: Laquinimod
A tablet immunomodulator studied in large clinical trials for multiple sclerosis. In 2014 the European Medicines Agency confirmed its refusal of authorisation, and development for this disease was later stopped.
Did you know?Its multiple sclerosis trials had musical names: ALLEGRO, BRAVO, CONCERTO and ARPEGGIO, the last one devoted to the primary progressive form.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Laquinimod family
Active ingredientLaquinimodCat. No. P-L018-001CAS 248281-84-7
Isotopically labelledLaquinimod-d5Cat. No. P-L018-003CAS 1214267-09-0
Isotopically labelledLaquinimod-d5 Sodium SaltCat. No. P-L018-004CAS 1354744-14-1
ImpurityPaquinimodCat. No. P-L018-005CAS 248282-01-1
ImpurityTasquinimodCat. No. P-L018-006CAS 254964-60-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.