Active ingredientLasofoxifeneCat. No. P-L023-001CAS 180916-16-9
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Stable isotope labelled · Lasofoxifene family
Pharmaceutical analytical standardLasofoxifene-d4
Synonyms: Rac Lasofoxifene-d4
- Cat. No.
- P-L023-005
- CAS
- 1126626-61-6
- Alternative CAS
- 180916-16-9 (unlabelled form)
- 180915-78-0 (unlabelled form)
- 190791-29-8 (unlabelled form, tartrate)
- 180915-85-9 (unlabelled form, hydrochloride)
- Formula
- C28H27D4NO2
- Molecular weight
- 417.59 g/mol
- Category
- Stable isotope labelled
Family: Lasofoxifene
A naphthalene-based selective oestrogen receptor modulator (SERM), authorised in the European Union in 2009 for postmenopausal osteoporosis; it was later also studied in breast cancer.
Did you know?It binds the oestrogen receptor alpha with an affinity comparable to that of oestradiol, the natural hormone, and at least ten times higher than that of tamoxifen.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Lasofoxifene family
Active ingredientLasofoxifeneCat. No. P-L023-001CAS 180916-16-9
Active ingredientLasofoxifene SulfateCat. No. P-L023-002CAS 1048953-96-3
MetaboliteLasofoxifene glucuronideCat. No. P-L023-003CAS 1048953-95-2
Isotopically labelledLasofoxifene Impurity 1-d4Cat. No. P-L023-004
Isotopically labelledLasofoxifene-d5Cat. No. P-L023-006
Isotopically labelledrac-Lasofoxifene-d5Cat. No. P-L023-009
Impurity1-PyrrolidineethanolCat. No. P-L023-010CAS 2955-88-6
Impurityrac-Lasofoxifene-2-OxideCat. No. P-L023-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.