ImpurityLatrepirdine Impurity 1Cat. No. P-L026-002CAS 23224-24-0
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Active ingredient · Latrepirdine family
Pharmaceutical analytical standardLatrepirdine DiHCl
Synonyms: Dimebon dihydrochloride, Dimebolin dihydrochloride
- Cat. No.
- P-L026-001
- CAS
- 97657-92-6
- Alternative CAS
- 3613-73-8 (free base)
- 1227953-42-5 (free base)
- 14292-23-0 (hydrochloride)
- 1186653-04-2 (hydrate)
- Formula
- C21H25N3·2HCl
- Molecular weight
- 392.37 g/mol
- Category
- Active ingredient (API)
An antihistamine that entered clinical use in Russia in 1983, also known as dimebolin. It was later tested for Alzheimer's disease and Huntington's disease, but the phase III trials, completed between 2010 and 2012, did not confirm its efficacy.
Did you know?Its 'second life' began in 2000 with Russian animal studies suggesting a protective effect on brain cells; unlike many older antihistamines, it also has no anticholinergic effects.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Latrepirdine family
ImpurityLatrepirdine Impurity 1Cat. No. P-L026-002CAS 23224-24-0
ImpurityLatrepirdine Impurity 2Cat. No. P-L026-003CAS 1147893-81-9
ImpurityLatrepirdine N-OxideCat. No. P-L026-004CAS 1147893-84-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.