Active ingredientLedipasvirCat. No. P-L029-001CAS 1256388-51-8
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Impurity or related compound · Ledipasvir family
Pharmaceutical analytical standardLedipasvir Impurity 5
Synonyms: [2-[(1R,3S,4S)-2-[(2-Methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]boronic acid
- Cat. No.
- P-L029-009
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C18H24BN3O4
- Molecular weight
- 357.22 g/mol
- Category
- Impurity or related compound
Family: Ledipasvir
An antiviral that inhibits the NS5A protein of the hepatitis C virus, approved in 2014 in a fixed combination with sofosbuvir for chronic hepatitis C.
Did you know?Together with sofosbuvir it formed the first combination pill approved by the FDA for hepatitis C, and the first regimen that did not require interferon or ribavirin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ledipasvir family
Active ingredientLedipasvirCat. No. P-L029-001CAS 1256388-51-8
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ImpurityLedipasvir Impurity 1Cat. No. P-L029-005
ImpurityLedipasvir Impurity 2Cat. No. P-L029-006
ImpurityLedipasvir Impurity 3Cat. No. P-L029-007
ImpurityLedipasvir Impurity 4Cat. No. P-L029-008CAS 1256387-87-7
ImpurityLedipasvir Impurity 6Cat. No. P-L029-010CAS 1441670-89-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.