Active ingredientLevothyroxine SodiumCat. No. P-L060-001CAS 25416-65-3
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Pharmacopoeial impurity · Levothyroxine family
Pharmaceutical analytical standardLevothyroxine EP Impurity B
- Cat. No.
- P-L060-003
- CAS
- 1628720-66-0
- Alternative CAS
- N/A
- Formula
- C15H11ClI3NO4
- Molecular weight
- 685.42 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Levothyroxine
The synthetic form of thyroxine (T4), the thyroid hormone, used in hypothyroidism; thyroxine was isolated in 1914 by Edward Kendall.
Did you know?In the United States it has for years been among the most prescribed medicines of all, and its dose is adjusted in micrograms: even small differences matter.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Levothyroxine family
Active ingredientLevothyroxine SodiumCat. No. P-L060-001CAS 25416-65-3
MetaboliteLevothyroxine sulfateCat. No. P-L060-002CAS 77074-49-8
Pharmacopoeial impurityLevothyroxine EP Impurity FCat. No. P-L060-004CAS 911661-90-0
Pharmacopoeial impurityLevothyroxine EP Impurity HCat. No. P-L060-005CAS 2055-97-2
Pharmacopoeial impurityLevothyroxine EP Impurity ICat. No. P-L060-006CAS 2016-06-0
Pharmacopoeial impurityLevothyroxine EP Impurity JCat. No. P-L060-007CAS 4604-41-5
Pharmacopoeial impurityLevothyroxine EP Impurity J HClCat. No. P-L060-008
Pharmacopoeial impurityLevothyroxine EP Impurity KCat. No. P-L060-009CAS 5817-39-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.