ImpurityLobaplatin Impurity 1Cat. No. P-L077-002CAS 1240256-76-1
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Active ingredient · Lobaplatin family
Pharmaceutical analytical standardLobaplatin
Synonyms: Lobaplatin (trans), NSC 741422, cis-(trans-1,2-cyclobutanebis(methylamine))((s)-lactato-o1,o1)platinum
- Cat. No.
- P-L077-001
- CAS
- 135558-11-1
- Alternative CAS
- 181486-56-6 (dihydrochloride)
- 160707-95-9 (other form)
- 131374-93-1 (alternative CAS, same compound)
- Formula
- C9H18N2O3Pt
- Molecular weight
- 397.33 g/mol
- Category
- Active ingredient (API)
A third-generation platinum anticancer drug, a relative of cisplatin, synthesised in Germany in 1990 and later approved in China, where it is used for small cell lung cancer, metastatic breast cancer and chronic myeloid leukaemia.
Did you know?In its structure the platinum atom is bound to a lactate molecule, the same one that builds up in muscles during exercise: when it detaches in the body it releases the form that attacks the DNA of cancer cells.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Lobaplatin family
ImpurityLobaplatin Impurity 1Cat. No. P-L077-002CAS 1240256-76-1
Impuritycis-1,2-Cyclobutanedimethanamine dihydrochlorideCat. No. P-L077-003CAS 206991-53-9
ImpurityLobaplatin Impurity 2 HydrochlorideCat. No. P-L077-013CAS 181486-56-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.