Active ingredientLubiprostoneCat. No. P-L102-002CAS 136790-76-6
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Impurity or related compound · Lubiprostone family
Pharmaceutical analytical standardLubiprostone Impurity 12
- Cat. No.
- P-L102-022
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C20H32F2O5
- Molecular weight
- 390.47 g/mol
- Category
- Impurity or related compound
Family: Lubiprostone
An activator of the ClC-2 chloride channels of the intestinal wall, which draws fluid into the gut and softens the stool: approved in the United States in 2006 for chronic idiopathic constipation.
Did you know?It is a bicyclic fatty acid derived from prostaglandin E1: it belongs to a series of 'functional fatty acids' discovered by Japanese researcher Ryuji Ueno.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Lubiprostone family
Active ingredientLubiprostoneCat. No. P-L102-002CAS 136790-76-6
MetaboliteLubiprostone M14 MetaboliteCat. No. P-L102-004CAS 1246812-13-4
Isotopically labelled15-Hydroxy Lubiprostone-d4Cat. No. P-L102-005
Isotopically labelledLubiprostone-d4Cat. No. P-L102-006
Isotopically labelledLubiprostone-d7Cat. No. P-L102-007CAS 1217675-13-2
Impurity15-Hydroxy LubiprostoneCat. No. P-L102-008CAS 475992-30-4
Impurity11-Deoxy-10,11-didehydro LubiprostoneCat. No. P-L102-009CAS 2196182-47-3
Impurity11-Deoxy LubiprostoneCat. No. P-L102-010CAS 321457-71-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.