Active ingredientMaprotiline HClCat. No. P-M007-001CAS 10347-81-6
Drag to rotate
Pharmacopoeial impurity · Maprotiline family
Pharmaceutical analytical standardMaprotiline EP Impurity B Hydrochloride
Synonyms: Maprotiline EP impurity B HCl, Maprotiline Impurity B HCl
- Cat. No.
- P-M007-004
- CAS
- 2724727-05-1
- Alternative CAS
- 1648814-39-4 (free base)
- Formula
- C39H41N·HCl
- Molecular weight
- 560.22 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Maprotiline
An antidepressant that mainly blocks the reuptake of noradrenaline, patented in 1966 and introduced into therapy in 1974 for depression, especially when accompanied by anxiety or agitation.
Did you know?It was the first tetracyclic antidepressant: its fourth ring is formed by an ethylene bridge spanning the central ring of an anthracene core.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Maprotiline family
Active ingredientMaprotiline HClCat. No. P-M007-001CAS 10347-81-6
Pharmacopoeial impurityMaprotiline EP Impurity DCat. No. P-M007-002CAS 38982-14-8
Pharmacopoeial impurityMaprotiline EP Impurity ACat. No. P-M007-003CAS 38849-09-1
Pharmacopoeial impurityMaprotiline EP Impurity C HClCat. No. P-M007-005CAS 92202-51-2
Pharmacopoeial impurityMaprotiline EP Impurity D HydrochlorideCat. No. P-M007-006CAS 38849-14-8
Pharmacopoeial impurityMaprotiline EP Impurity E HydrochlorideCat. No. P-M007-007CAS 23941-45-9
Isotopically labelledMaprotiline EP Impurity C-d4 HClCat. No. P-M007-008
Isotopically labelledMaprotiline-d3 HClCat. No. P-M007-009CAS 1329496-63-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.