Impurity or related compound · Maribavir family
Pharmaceutical analytical standardMaribavir Impurity 1
Synonyms: 5,6-Dichloro-1-beta-L-ribofuranosyl-1H-benzimidazol-2-amine
- Cat. No.
- P-M010-003
- CAS
- 176161-52-7
- Alternative CAS
- N/A
- Formula
- C12H13Cl2N3O4
- Molecular weight
- 334.15 g/mol
- Category
- Impurity or related compound
Family: Maribavir
An oral antiviral against cytomegalovirus that blocks the viral kinase pUL97, regarded by the FDA as first in its class. Approved in the United States in 2021 and in Europe in 2022 for post-transplant infections that do not respond to other treatments.
Did you know?It is a benzimidazole linked to a 'mirror-image' sugar: it contains ribose in the L form, whereas the natural nucleosides of DNA and RNA use the D form.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
More products in the Maribavir family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
