Active ingredientMedroxyprogesterone AcetateCat. No. P-M029-001CAS 71-58-9
Drag to rotate
Pharmacopoeial impurity · Medroxyprogesterone family
Pharmaceutical analytical standardMedroxyprogesterone Acetate EP Impurity H
Synonyms: Chlormadinone Acetate EP Impurity G, Megestrol Acetate EP Impurity K, 17-alpha-Acetoxy Progesterone, 17-alpha-Acetoxy Progesterone, Hydroxyprogesterone acetate, Prodox acetate, Acetoxyprogesterone, NSC 12191, Megestrol acetate impurity k (ep impurity), Medroxyprogesterone acetate impurity h (ep impurity), Medroxyprogesterone Acetate Impurity H, Prokan, Megestrol Acetate Impurity K
- Cat. No.
- P-M029-028
- CAS
- 302-23-8
- Alternative CAS
- N/A
- Formula
- C23H32O4
- Molecular weight
- 372.50 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Medroxyprogesterone
A synthetic progestin discovered in 1956 and in use since 1959, used as medroxyprogesterone acetate for menstrual disorders, menopausal hormone therapy, contraception and some hormone-dependent tumours.
Did you know?It was developed partly because for decades natural progesterone could not be taken by mouth. In its injectable 'depot' form, used as a contraceptive since 1969, a single injection lasts about three months.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Chlormadinone acetate impurity G CRSEP Y0001656
More products in the Medroxyprogesterone family
Active ingredientMedroxyprogesterone AcetateCat. No. P-M029-001CAS 71-58-9
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity ACat. No. P-M029-002CAS 984-47-4
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity BCat. No. P-M029-003CAS 520-85-4
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity CCat. No. P-M029-004
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity DCat. No. P-M029-005CAS 2242-65-1
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity ECat. No. P-M029-006CAS 32634-95-0
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity FCat. No. P-M029-007CAS 69688-15-9
Pharmacopoeial impurityMedroxyprogesterone Acetate EP Impurity ICat. No. P-M029-008CAS 3112446-15-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.