Active ingredientMemantineCat. No. P-M043-001CAS 19982-08-2
Drag to rotate
Pharmacopoeial impurity · Memantine family
Pharmaceutical analytical standardMemantine Related Compound F Hydrochloride
Synonyms: Memantine Related Compound F HCl
- Cat. No.
- P-M043-023
- CAS
- 356572-08-2
- Alternative CAS
- 63971-25-5 (free base)
- Formula
- C12H21NO·HCl
- Molecular weight
- 231.76 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Memantine
An NMDA glutamate receptor antagonist used in moderate to severe Alzheimer's disease: synthesised in the 1960s, it was approved in Europe in 2002 and in the United States in 2003.
Did you know?It was first made as a possible antidiabetic, but it did not lower blood sugar; its cage-like core, adamantane, is named after diamond because it repeats diamond's arrangement of carbon atoms.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Memantine family
Active ingredientMemantineCat. No. P-M043-001CAS 19982-08-2
Active ingredientMemantine HydrochlorideCat. No. P-M043-002CAS 41100-52-1
Pharmacopoeial impurityMemantine USP Related Compound ACat. No. P-M043-003CAS 702-79-4
Pharmacopoeial impurityMemantine USP Related Compound BCat. No. P-M043-004CAS 707-37-9
Pharmacopoeial impurityMemantine USP Related Compound CCat. No. P-M043-005CAS 707-36-8
Pharmacopoeial impurityMemantine USP Related Compound DCat. No. P-M043-006CAS 941-37-7
Pharmacopoeial impurityMemantine USP Related Compound ECat. No. P-M043-007CAS 351329-88-9
Pharmacopoeial impurityMemantine USP Related Compound F (Free Form)Cat. No. P-M043-008CAS 63971-25-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.