Active ingredientMesalazineCat. No. P-M063-001CAS 89-57-6
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Pharmacopoeial impurity · Mesalazine family
Pharmaceutical analytical standardMesalazine EP Impurity E
Synonyms: 4-Aminosalicylic Acid, 4-amino-2-hydroxybenzoic acid, Aminosalicylic acid, p-aminosalicylic acid, Paramycin, Parasal, Paser, Parasalindon, Deapasil, Apacil, Gabbropas, Parasalicil, Aminopar, Entepas, Pamacyl, Pasalon, Pasnodia, Pasolac, Propasa, Osacyl, Pasara, Pasem, Pasmed, Pasa, Para-Pas, Sanipirol-4, APAS, Benzoic acid, 4-amino-2-hydroxy-, PASK, Aminox, Pasdium, Hellipidyl, Para-Amino salicylic acid, Pascorbic, PAS (acid), Aminosalicylate, Aminosalyl, Helipidyl, Paser Granules, Salicylic acid, 4-amino-, Granupas, NSC 2083, Acid, Aminosalicylic, Alumino 4 Aminosalicylic Acid, Rezipas, Pamisyl, Kyselina p-aminosalicylova, Amino-pas, Sanipriol-4, Benzoic acid, 4-aminohydroxy-, Aminosalicylic, gamma-Aminosalicylate, Para-amino-salicyclic acid, Salicyclic acid, 4-amino-, Neopasalate component aminosalicylic acid
- Cat. No.
- P-M063-006
- CAS
- 65-49-6
- Alternative CAS
- 133-15-3 (calcium salt)
- 6059-16-1 (calcium salt)
- 94022-09-0 (zinc salt)
- 94233-03-1 (magnesium salt)
- 123465-67-8 (magnesium salt)
- 133-10-8 (sodium salt)
- 8031-28-5 (sodium salt)
- 1374221-08-5 (calcium salt hydrate)
- 6018-18-4 (hydrochloride)
- 6018-19-5 (sodium salt hydrate)
- 133-09-5 (potassium salt)
- 860507-80-8 (hydrate)
- 769-50-6 (alternative CAS, same compound)
- Formula
- C7H7NO3
- Molecular weight
- 153.14 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Mesalazine
5-aminosalicylic acid, an anti-inflammatory that acts directly on the lining of the gut: in 1977 it was recognised as the active part of sulfasalazine and it is now a mainstay of ulcerative colitis treatment.
Did you know?Sulfasalazine, its parent drug, was developed between the late 1930s and the early 1940s by Nanna Svartz, Sweden's first female professor of medicine, with rheumatoid arthritis in mind.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Mesalazine family
Active ingredientMesalazineCat. No. P-M063-001CAS 89-57-6
Pharmacopoeial impurity4-AminophenolCat. No. P-M063-002CAS 123-30-8
Pharmacopoeial impurityMesalazine EP Impurity BCat. No. P-M063-003CAS 591-27-5
Pharmacopoeial impurityMesalazine EP Impurity CCat. No. P-M063-004CAS 95-55-6
Pharmacopoeial impurityMesalazine EP Impurity DCat. No. P-M063-005CAS 99-05-8
Pharmacopoeial impurityMesalazine EP Impurity FCat. No. P-M063-007CAS 570-23-0
Pharmacopoeial impurityMesalazine EP Impurity F HClCat. No. P-M063-008CAS 17839-48-4
Pharmacopoeial impurityMesalazine EP Impurity GCat. No. P-M063-009CAS 490-79-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.