Active ingredient · Mestranol family
Pharmaceutical analytical standardMestranol
Synonyms: Norquen, Ovastol, Menophase, Ethynylestradiol 3-methyl ether, Ethynylestradiol methyl ether, Compound 33355, Ethinylestradiol 3-methyl ether, Ethynyloestradiol 3-methyl ether, NSC 84032, Devocin, EE(sub3)ME, Inostral, Component of Norinyl, Component of Ortho-Novum, delta-MVE, Ethinyloestradiol 3-methyl ether, Component of Ovulen, Component of Norquen, Inostral (steroid), Caswell No. 547A, EPA Pesticide Chemical Code 115401
- Cat. No.
- P-M066-001
- CAS
- 72-33-3
- Alternative CAS
- N/A
- Formula
- C21H26O2
- Molecular weight
- 310.44 g/mol
- Category
- Active ingredient (API)
A synthetic oestrogen, the methyl ether of ethinylestradiol, into which the liver converts it: discovered in 1956 and in use since 1957, it was the oestrogen of the first combined contraceptive pill, together with the progestin noretynodrel.
Did you know?It was found almost by chance: the first batches of noretynodrel contained 1-2% of it as a manufacturing impurity, and when it was removed irregular bleeding appeared. So it was added back on purpose.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Mestranol CRSEP M0600000
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.