Active ingredient · Methyl Nicotinate family
Pharmaceutical analytical standardMethyl Nicotinate
Synonyms: methyl pyridine-3-carboxylate, FEMA No. 3709, Vitathone, NSC 13126, Nikomet, Nicometh, m-(Methoxycarbonyl)pyridine, Pyridine, 3-methoxycarbonyl-, Nicotinato di metile, NSC 403799
- Cat. No.
- P-M090-001
- CAS
- 93-60-7
- Alternative CAS
- N/A
- Formula
- C7H7NO2
- Molecular weight
- 137.14 g/mol
- Category
- Active ingredient (API)
The methyl ester of nicotinic acid (niacin, vitamin B3): applied to the skin it widens small blood vessels, producing warmth and redness, which is why it is used as a rubefacient in sprays and creams for muscle and joint pain.
Did you know?It has been proposed as a marker of tuberculosis: in 2009 a study measured different levels in patients' breath, because the bacillus produces nicotinic acid.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Methyl nicotinate CRSEP Y0000398
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.