Pharmacopoeial impurityMethylergometrine EP Impurity ACat. No. P-M094-002CAS 82-58-6
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Active ingredient · Methylergometrine family
Pharmaceutical analytical standardMethylergometrine Maleate
Synonyms: Methergine, Methylergonovine maleate, Maleic acid, methyl ergonovine, NSC 757104, Methyl Ergonovine Maleate Salt, Erezingen, Methylergobasine maleate, USAF uctl-8, Methergine maleate, Pharmakon1600-01500404, Ergoline-8-carboxamide, 9,10-didehydro-n-(1-(hydroxymethyl)propyl)-6-methyl-, (8beta(s))-, (z)-2-butenedioate
- Cat. No.
- P-M094-001
- CAS
- 57432-61-8
- Alternative CAS
- 113-42-8 (free base)
- 7054-07-1 (alternative CAS, same compound)
- Formula
- C20H25N3O2·C4H4O4
- Molecular weight
- 455.51 g/mol
- Category
- Active ingredient (API)
A semi-synthetic derivative of ergometrine, the ergot alkaloid isolated in 1935 from the fungus Claviceps purpurea: it makes the uterus contract and is used mainly to prevent and control bleeding after childbirth.
Did you know?Besides obstetrics, it has been used against migraine and even as a test to recognise angina caused by spasms of the coronary arteries.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Methylergometrine for system suitability CRSEP Y0000777
- Methylergometrine maleate CRSEP Y0000776
More products in the Methylergometrine family
Pharmacopoeial impurityMethylergometrine EP Impurity ACat. No. P-M094-002CAS 82-58-6
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Pharmacopoeial impurityMethylergometrine EP Impurity ICat. No. P-M094-010CAS 724767-21-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.