Active ingredientMitoxantroneCat. No. P-M150-001CAS 65271-80-9
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Impurity or related compound · Mitoxantrone family
Pharmaceutical analytical standardMitoxantrone Impurity 3
Synonyms: 5,8,9,10-Tetrahydroxy-2,3-dihydroanthracene-1,4-dione, NSC 23122, Leucotetrahydroxyanthraquinone
- Cat. No.
- P-M150-015
- CAS
- 81-59-4
- Alternative CAS
- 68929-10-2 (sodium salt)
- Formula
- C14H10O6
- Molecular weight
- 274.23 g/mol
- Category
- Impurity or related compound
Family: Mitoxantrone
An anticancer drug of the anthracenedione class, related to the anthracyclines, approved in 1987 and used against certain leukaemias; it is also used in some forms of multiple sclerosis.
Did you know?It can turn the urine blue-green for about 24 hours after administration and sometimes give the whites of the eyes a temporary bluish tint.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Mitoxantrone family
Active ingredientMitoxantroneCat. No. P-M150-001CAS 65271-80-9
Active ingredientMitoxantrone DiHClCat. No. P-M150-002CAS 70476-82-3
Pharmacopoeial impurityMitoxantrone EP Impurity BCat. No. P-M150-003CAS 80189-44-2
Pharmacopoeial impurityMitoxantrone EP Impurity CCat. No. P-M150-004CAS 1796928-50-1
Pharmacopoeial impurityMitoxantrone EP Impurity DCat. No. P-M150-005CAS 137132-70-8
Pharmacopoeial impurityMitoxantrone EP Impurity D HydrochlorideCat. No. P-M150-006CAS 261164-09-4
Isotopically labelledMitoxantrone-d8Cat. No. P-M150-007CAS 1189974-82-0
NitrosamineN1-Nitroso MitoxantroneCat. No. P-M150-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.