Pharmacopoeial impurityMometasone Furoate EP Impurity ACat. No. P-M162-002CAS 83880-65-3
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Active ingredient · Mometasone family
Pharmaceutical analytical standardMometasone Furoate
Synonyms: Asmanex, Elocon, Sinuva, Asmanex HFA, Asmanex Twisthaler, Propel Contour, Propel mini, Childrens Nasonex, Twisthaler, Asmanex, Nasonex, Monovo, Danitin, Ecural, Elomet, Elocone, Flumeta, Nosorex, Rimelon, Ovixan, Momethasone furoate, Momethasone fuorate
- Cat. No.
- P-M162-001
- CAS
- 83919-23-7
- Alternative CAS
- 141646-00-6 (hydrate)
- Formula
- C27H30Cl2O6
- Molecular weight
- 521.43 g/mol
- Category
- Active ingredient (API)
A synthetic corticosteroid patented in 1981 and in use since 1987: it is applied to the skin for eczema and psoriasis, sprayed into the nose for allergic rhinitis and nasal polyps, and inhaled to prevent asthma.
Did you know?Mometasone itself has never been marketed: it is always used as its ester, mometasone furoate. Besides its corticosteroid action, it is also a very potent activator of the progesterone receptor.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Mometasone FuroateBP 768
- Mometasone furoate CRSEP M2900000
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Pharmacopoeial impurityMometasone Furoate EP Impurity HCat. No. P-M162-009CAS 148596-90-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.