Active ingredientRosiglitazoneCat. No. P-R087-001CAS 122320-73-4
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Impurity or related compound · Rosiglitazone family
Pharmaceutical analytical standardN-(1,2-Dicarboxyethyl) Rosiglitazone
Synonyms: Rosiglitazone N-(2-Succinic Acid), Butanedioic acid, 2-(5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-dioxo-3-thiazolidinyl)-
- Cat. No.
- P-R087-016
- CAS
- 956239-35-3
- Alternative CAS
- N/A
- Formula
- C22H23N3O7S
- Molecular weight
- 473.50 g/mol
- Category
- Impurity or related compound
Family: Rosiglitazone
An antidiabetic of the glitazone (thiazolidinedione) class, approved in 1999 in the United States and in 2000 in Europe for type 2 diabetes: it makes cells more sensitive to insulin.
Did you know?It acts on the nuclear receptor PPAR-gamma, found mainly in fat tissue, where it drives the formation of new fat cells and the storage of fats.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Rosiglitazone family
Active ingredientRosiglitazoneCat. No. P-R087-001CAS 122320-73-4
Active ingredientRosiglitazone MaleateCat. No. P-R087-002CAS 155141-29-0
Pharmacopoeial impurityRosiglitazone Maleate EP Impurity ACat. No. P-R087-003CAS 1797979-55-5
Isotopically labelled5-Hydroxy Rosiglitazone-d4Cat. No. P-R087-004CAS 1246817-46-8
Isotopically labelled5-Hydroxy rosiglitazone-d4 sulphate potassium saltCat. No. P-R087-006
Isotopically labelledN-Desmethyl rosiglitazone-d4Cat. No. P-R087-007CAS 1215407-67-2
Isotopically labelledRosiglitazone-d3Cat. No. P-R087-008CAS 1132641-22-5
ImpurityRosiglitazone Impurity 1Cat. No. P-R087-009CAS 1924671-90-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.