Isotopically labelledBenztropine-13C-d3 MesylateCat. No. P-B039-002
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Impurity or related compound · Benzatropine family
Pharmaceutical analytical standardN-Desmethyl Benztropine HCl
Synonyms: N-Desmethyl-benzotropine Hydrochloride
- Cat. No.
- P-B039-007
- CAS
- 25471-67-4
- Alternative CAS
- 28404-87-7 (free base)
- Formula
- C20H24ClNO
- Molecular weight
- 329.87 g/mol
- Category
- Impurity or related compound
Family: Benzatropine
A centrally acting anticholinergic with antihistamine activity, approved in the United States in 1954: it is used in parkinsonism and dystonia and to reduce movement disorders caused by antipsychotics.
Did you know?A large-scale screen of known molecules found that it makes oligodendrocytes mature, the cells that produce myelin: in animal models of multiple sclerosis it promoted remyelination.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Desmethyl Benzatropine HydrochlorideBP 689
More products in the Benzatropine family
Isotopically labelledBenztropine-13C-d3 MesylateCat. No. P-B039-002
Isotopically labelledBenztropine-d5Cat. No. P-B039-003
Isotopically labelledN-Desmethyl Benztropine-d5Cat. No. P-B039-004
ImpurityBenztropine HBrCat. No. P-B039-005CAS 6148-20-5
ImpurityBenztropine MesylateCat. No. P-B039-006CAS 132-17-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.