Active ingredientMetoprolol FumarateCat. No. P-M110-001CAS 80274-67-5
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Nitrosamine · Metoprolol family
Pharmaceutical analytical standardN-Nitroso Metoprolol
Synonyms: 1-[4-(2-Methoxyethyl)phenoxy]-3-[nitroso(propan-2-yl)amino]propan-2-ol, N-(2-hydroxy-3-(4-(2-methoxyethyl)phenoxy)propyl)-N-isopropylnitrous amide
- Cat. No.
- P-M110-018
- CAS
- 138768-62-4
- Alternative CAS
- 134720-05-1 (alternative CAS, same compound)
- Formula
- C15H24N2O4
- Molecular weight
- 296.37 g/mol
- Category
- Nitrosamine
Family: Metoprolol
A cardioselective beta blocker synthesised in Sweden in 1969 and on the market since 1975: it slows the heart and reduces its workload, and is used for high blood pressure, angina, arrhythmias and heart failure.
Did you know?To find it, Swedish researchers Bengt Åblad and Enar Carlsson synthesised and screened about 400 substances, looking for a beta blocker that would act mainly on the heart.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Metoprolol family
Active ingredientMetoprolol FumarateCat. No. P-M110-001CAS 80274-67-5
Active ingredientMetoprolol SuccinateCat. No. P-M110-002CAS 98418-47-4
Active ingredientMetoprolol TartrateCat. No. P-M110-003CAS 56392-17-7
Pharmacopoeial impurityMetoprolol EP Impurity ACat. No. P-M110-004CAS 109632-08-8
Pharmacopoeial impurityMetoprolol EP Impurity BCat. No. P-M110-005CAS 56718-71-9
Pharmacopoeial impurityMetoprolol EP Impurity DCat. No. P-M110-006CAS 62572-90-1
Pharmacopoeial impurityMetoprolol EP Impurity ECat. No. P-M110-007CAS 163685-38-9
Pharmacopoeial impurityMetoprolol EP Impurity FCat. No. P-M110-008CAS 7695-63-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.