Pharmacopoeial impurity(1R,2R)-PseudoephedrineCat. No. P-P231-002CAS 321-97-1
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Nitrosamine · Pseudoephedrine family
Pharmaceutical analytical standardN-Nitroso Pseudoephedrine
Synonyms: alpha-(1-(Methylnitrosoamino)ethyl)benzenemethanol, N-(1-hydroxy-1-phenylpropan-2-yl)-N-methylnitrous amide, alpha-(1-(N-Methyl-N-nitrosoamino)ethyl)benzyl alcohol, Ephedrine Impurity N1, alpha-(1-(Methylnitrosamino)ethyl)benzyl alcohol stereoisomer, Benzyl alcohol, alpha-(1-(methylnitrosamino)ethyl)-, stereoisomer, BENZYL ALCOHOL, alpha-(1-(N-METHYL-N-NITROSOAMINO)ETHYL)-, N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide, N-Nitroso Pseudoephedrine (N-Nitroso Ephedrine HCl EP Impurity B)
- Cat. No.
- P-P231-006
- CAS
- 1850-88-0
- Alternative CAS
- N/A
- Formula
- C10H14N2O2
- Molecular weight
- 194.23 g/mol
- Category
- Nitrosamine
Family: Pseudoephedrine
An ephedra alkaloid and stereoisomer of ephedrine, isolated in Germany in 1889 by the chemists Ladenburg and Oelschlägel: it narrows the blood vessels of the nasal lining and is used as a decongestant for a blocked nose due to colds and sinusitis.
Did you know?Ephedra, or ma huang, has been used in traditional Chinese medicine for thousands of years, but the decongestant effect of pseudoephedrine was only described in 1927, through animal experiments.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pseudoephedrine family
Pharmacopoeial impurity(1R,2R)-PseudoephedrineCat. No. P-P231-002CAS 321-97-1
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NitrosamineN-Nitroso ent-PseudoephedrineCat. No. P-P231-005CAS 58800-96-7
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Active ingredient(+)-Pseudoephedrine HydrochlorideCat. No. P-P231-008CAS 345-78-8
ImpurityChloropseudoephedrine HClCat. No. P-P231-009CAS 94133-42-3
ImpurityN-Formyl EphedrineCat. No. P-P231-010CAS 67844-53-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.